This study demonstrates the sensitivity of MRI and magnetic resonance spectroscopy (MRS) as a biomarker to detect the effects of corticosteroids on leg muscles. This underlines the potential of MRI/MRS as a biomarker in clinical trials assessing therapeutic interventions for Duchenne muscular dystrophy.
This study demonstrates a strong relationship between lower extremity MRI and functional measures over a period of 48 months. In addition, MR biomarkers of proximal muscles predicted future ambulatory and clinical milestone status
Magnetic Resonance Imaging Studies in Duchenne Muscular Dystrophy: Linking Findings to the Physical Therapy Clinic. Phys Ther.
This article describes how MRI has impacted our understanding of Duchenne muscular dystrophy and discusses implications for physical therapy care for individuals with this rare disease.